Article
euL1db: the European database of L1HS retrotransposon insertions in humans.
Nucleic acids research - 1 Jan 2015
Mir Ashfaq A, Philippe Claude, Cristofari Gaël
Abstract excerpt
Retrotransposons account for almost half of our genome. They are mobile genetics elements-also known as jumping genes--but only the L1HS subfamily of Long Interspersed Nuclear Elements (LINEs) has retained the ability to jump autonomously in modern humans. Their mobilization in germline--but also some somatic tissues--contributes to human genetic diversity and to diseases, such as cancer. Here, we present euL1db,...
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