Article

Variable susceptibility of intestinal organoid-derived monolayers to SARS-CoV-2 infection

2021-07-16

Abstract excerpt

<h4>ABSTRACT</h4> Gastrointestinal effects associated with COVID-19 are highly variable for reasons that are not understood. In this study, we used intestinal organoid-derived cultures differentiated from primary human specimens as a model to examine inter-individual variability. Infection of intestinal organoids derived from different donors with SARS-CoV-2 resulted in orders of magnitude differences in virus re...

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Literature Corpus work: fe9482e8-5af3-5d5b-9248-baf8f0da50b2
DOI: 10.1101/2021.07.16.452680

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