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Individual Host Variation in Single-cell Responses to Enteroaggregative <i>Escherichia coli</i> Infection Modeled with Human Colon Organoids

2025-10-24

Abstract excerpt

<h4>ABSTRACT</h4> Enteroaggregative Escherichia coli (EAEC) is a leading cause of diarrhea disease worldwide. Interestingly, EAEC disease outcomes vary dramatically among infected individuals, ranging from asymptomatic colonization to acute and chronic diarrhea. While previous research has focused on EAEC virulence factors, emerging evidence suggests that host genetic and cellular background may be equally impor...

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Literature Corpus work
2e94ac71-63be-52eb-9079-5c17dac1fd0b
DOI
10.1101/2025.10.24.684350
Open publication

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Individual Host Variation in Single-cell Responses to Enteroaggregative <i>Escherichia coli</i> Infection Modeled with Human Colon OrganoidsDOI 10.1101/2025.10.24.684350
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