Article

SARS-CoV-2 Productively Infects Human Gut Enterocytes

2020-04-25

Abstract excerpt

COVID-19, caused by SARS-CoV-2, is an influenza-like disease with a respiratory route of transmission, yet clinical evidence suggests that the intestine may present another viral target organ. Indeed, the SARS-CoV-2 receptor angiotensin converting enzyme 2 (ACE2) is highly expressed on differentiated enterocytes. In human small intestinal organoids, enterocytes were readily infected by SARS-CoV and SARS-CoV-2 as d...

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Literature Corpus work: c474021e-fc33-53d9-b8ff-36d12c98374e
DOI: 10.1101/2020.04.25.060350

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