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Human Pluripotent Stem Cell Derived Intestinal Organoids Model SARS-CoV-2 Infection Revealing a Common Epithelial Inflammatory Response

2020-11-24

Abstract excerpt

SARS-CoV-2 infection leading to COVID-19 usually results in respiratory disease, but extrapulmonary manifestations are of major clinical interest. Intestinal symptoms of COVID-19 are present in a significant number of patients, and include nausea, diarrhea, and viral RNA shedding in feces. Human induced pluripotent stem cell (iPSC) derived intestinal organoids (HIOs) represent an inexhaustible cellular resource th...

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Literature Corpus work
63a87588-ed5f-5661-8ad6-4b0a9527a195
DOI
10.2139/ssrn.3737106
Open publication

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