Article

Reduced SARS-CoV-2 infection and altered antiviral transcriptional response in IBD intestinal organoids

2023-06-05

Abstract excerpt

<h4>Summary</h4> IBD is characterized by altered immune reactions and infections are thought to trigger the chronic inflammatory response in IBD. The gut represents a productive reservoir for SARS-CoV-2 and the aforementioned factors together with immunosuppression used to treat IBD are likely influencing the outcomes of IBD patients in COVID-19. We used large and small intestinal organoids from IBD patients and c...

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Literature Corpus work: 2903bbf1-4f6a-5265-9ca6-421cac6184ef
DOI: 10.1101/2023.06.05.23290961

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