Article

Recapitulation of SARS-CoV-2 Infection and Cholangiocyte Damage with Human Liver Organoids

2020-03-17

Abstract excerpt

The newly emerged pandemic coronavirus, SARS-CoV-2, has posed a significant public health threat worldwide. However, the mode of virus transmission and tissue tropism is not well established yet. Recent findings of substantial liver damage in patients and ACE2+ cholangiocytes in healthy liver tissues prompted us to hypothesize that human liver ductal organoids could serve as a model to determine the susceptibility...

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Literature Corpus work: 2bc27667-b75f-50d8-a528-6b9cc5670759
DOI: 10.1101/2020.03.16.990317

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