Article

Atf3 links loss of epithelial polarity to defects in cell differentiation and cytoarchitecture

2017-11-05

Abstract excerpt

Interplay between apicobasal cell polarity modules and the cytoskeleton is critical for differentiation and integrity of epithelia. However, this coordination is poorly understood at the level of gene regulation by transcription factors. Here, we establish the Drosophila activating transcription factor 3 ( atf3 ) as a cell polarity response gene acting downstream of the membrane-associated Scribble polarity comp...

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Literature Corpus work: fe89cdd2-00ca-5b6b-afbe-22e5a2fa4a26
DOI: 10.1101/212969

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