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FAM83H couples keratin organization to Notch signaling during epidermal morphogenesis

2026-05-29

Abstract excerpt

Keratin intermediate filaments are essential for epidermal integrity, yet how keratin organization is coupled to the cell fate signaling that coordinates keratinocyte differentiation during epidermal morphogenesis remains poorly understood. Here, we identify FAM83H as a previously unrecognized regulator that links keratin cytoskeletal organization to epidermal cell fate decisions. Using mouse models and a human 3D...

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Literature Corpus work
97e4d986-6d16-5d70-bf1c-a95f5fb89f21
DOI
10.64898/2026.05.26.727959
Open publication

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FAM83H couples keratin organization to Notch signaling during epidermal morphogenesisDOI 10.64898/2026.05.26.727959
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