Article
Spatially resolved transcriptome profiles of mammalian kidneys illustrate the molecular complexity of functional nephron segments, cell-to-cell interactions and genetic variants
2020-09-30
Abstract excerpt
Understanding the molecular mechanisms underlying mammalian kidney function requires transcriptome profiling of the interplay between cells comprising nephron segments. Traditional transcriptomics requires cell dissociation, resulting in loss of the spatial context of gene expression within native tissue. To address this problem, we performed spatial transcriptomics (ST) to retain the spatial context of the transc...
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Identifiers and source
- Literature Corpus work
- d582a8ce-ba8a-5eb7-bfc2-547d3c11af2b
- DOI
- 10.1101/2020.09.29.317917