Article

Leveraging Multi-tissue, Single-Cell Atlases as Tools to Elucidate Shared Mechanisms of Immune-Mediated Inflammatory Diseases

2024-06-06

Abstract excerpt

The observation that certain therapeutic strategies for targeting inflammation benefit patients with distinct immune-mediated inflammatory diseases (IMIDs) is exemplified by the success of TNF blockade in conditions including rheumatoid arthritis, ulcerative colitis and skin psoriasis, albeit only for subsets of individuals with each condition. This suggests intersecting "nodes" in inflammatory networks at a molec...

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Literature Corpus work: fe580802-07d5-5c33-8f08-5b71eeb5b746
DOI: 10.20944/preprints202405.1276.v2

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