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Article

The Integrated Cellular and Molecular Landscape of Autoimmunity

2025-09-17

Abstract excerpt

<h4>Summary</h4> We performed a large-scale immunogenomic analysis of ∼13,000 transcriptomic profiles from 10 autoimmune diseases, integrating publicly available datasets from both blood and tissue. Using meta-analysis, we identified core immune mechanisms underlying autoimmunity, including strong interferon responses, inflammation, and adaptive immune suppression, alongside disease-specific signatures. To enhanc...

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Identifiers and source

Literature Corpus work
4dcb5b07-78c9-5dd0-b08e-39cfe1a311b0
DOI
10.1101/2025.09.12.675833
Open publication

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The Integrated Cellular and Molecular Landscape of AutoimmunityDOI 10.1101/2025.09.12.675833
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