Article

Anxiety induced by extra-hypothalamic BDNF deficiency instigates resistance to diet-induced obesity

2018-04-28

Abstract excerpt

<h4>SUMMARY</h4> Anxiety disorders are associated with body weight changes in humans. However, mechanisms underlying anxiety-related weight changes remain poorly understood. Using Emx1 Cre/+ mice, we deleted the gene for brain-derived neurotrophic factor (BDNF) in the cortex, hippocampus, and some parts of the amygdala. The resulting mutant mice displayed elevated anxiety levels and were markedly lean when fed...

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Literature Corpus work: fdd41a67-9c6a-5b06-b66b-6a4913a37222
DOI: 10.1101/309930

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