Article

Dorsomedial hypothalamic BDNF neurons integrate thermal afferent signals to control energy expenditure

2021-04-11

Abstract excerpt

Mutations in the gene brain-derived neurotrophic factor (BDNF) cause obesity in humans. BDNF signaling and its expressing neurons in the hypothalamus help control feeding, energy expenditure (EE), and physical activity. However, whether the BDNF neurons interact with another EE-regulating system, the thermoregulation circuitry, remains unclear. Here, we show that BDNF neurons in the dorsomedial hypothalamus (DMH)...

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Literature Corpus work: 774d5031-1eff-5a97-9133-bc18b46a9ebb
DOI: 10.1101/2021.04.11.439314

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