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Article

Molecular and neural bases underlying roles of BDNF in the control of body weight

1 Jan 2013

Abstract excerpt

Brain-derived neurotrophic factor (BDNF) is a potent regulator of neuronal development and synaptic plasticity that is fundamental to neural circuit formation and cognition. It is also involved in the control of appetite and body weight, with mutations in the genes for BDNF and its receptor, TrkB, resulting in remarkable hyperphagia and severe obesity in humans and mice. Recent studies have made significant...

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PMID: 23519010
DOI: 10.3389/fnins.2013.00037

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