Article
Emerging Insights into the Role of BDNF on Health and Disease in Periphery.
Biomolecules - 5 Apr 2024
Ichimura-Shimizu Mayuko, Kurrey Khuleshwari, Miyata Misaki, Dezawa Takuya, Tsuneyama Koichi, Kojima Masami
Abstract excerpt
Brain-derived neurotrophic factor (BDNF) is a growth factor that promotes the survival and growth of developing neurons. It also enhances circuit formation to synaptic transmission for mature neurons in the brain. However, reduced BDNF expression and single nucleotide polymorphisms (SNP) are reported to be associated with functional deficit and disease development in the brain, suggesting that BDNF is a crucial...
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