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An ancient polymorphic regulatory region within the BDNF gene associated with obesity modulates anxiety-like behaviour in mice and humans

2021-07-20

Abstract excerpt

Obesity and anxiety are morbidities notable for their increased impact on society during the recent COVID-19 pandemic. Understanding the mechanisms governing susceptibility to these conditions will increase quality of life and our resilience to future pandemics. In the current study we explored the function of a highly conserved regulatory region (BE5.1) within the BDNF gene that harbours a polymorphism strongly a...

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Identifiers and source

Literature Corpus work
c92574ad-4a4a-5305-91aa-950bbce8609f
DOI
10.1101/2021.07.20.452916
Open publication

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An ancient polymorphic regulatory region within the BDNF gene associated with obesity modulates anxiety-like behaviour in mice and humansDOI 10.1101/2021.07.20.452916
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