Article
BDNF-Val66Met variant and adolescent stress interact to promote susceptibility to anorexic behavior in mice.
Translational psychiatry - 5 Apr 2016
Madra M, Zeltser L M
Abstract excerpt
There is an urgent need to identify therapeutic targets for anorexia nervosa (AN) because current medications do not impact eating behaviors that drive AN's high mortality rate. A major obstacle to developing new treatments is the lack of animal models that recapitulate the pattern of disease onset typically observed in human populations. Here we describe a translational mouse model to study interactions between...
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