Article

Comparison of HAV and HCV infections <i>in vivo</i> and <i>in vitro</i> reveals distinct patterns of innate immune evasion and activation

2022-11-07

Abstract excerpt

<h4>ABSTRACT</h4> <h4>Objective</h4> Hepatitis A virus (HAV) infections are considered not to trigger an innate immune response in vivo , in contrast to hepatitis C virus (HCV). This lack of immune induction has been imputed to strong immune counteraction by HAV proteases 3CD and 3ABC. We aimed at elucidating the mechanisms of innate immune induction and counteraction by HAV and HCV in vivo and in vitro . <h...

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Literature Corpus work: fdc2e1f5-fdea-599d-8a23-d8c9aebc24fc
DOI: 10.1101/2022.11.07.515428

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