Article

Pooled PPIseq: screening the SARS-CoV-2 and human interface with a scalable multiplexed protein-protein interaction assay platform

2024-02-14

Abstract excerpt

P rotein- P rotein I nteractions ( PPI s) are a key interface between virus and host, and these interactions are important to both viral reprogramming of the host and to host restriction of viral infection. In particular, viral-host PPI networks can be used to further our understanding of the molecular mechanisms of tissue specificity, host range, and virulence. At higher scales, viral-host PPI screening could...

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Literature Corpus work: fdabda11-58d1-5c76-bf5f-0d557d8474fe
DOI: 10.1101/2024.02.13.580123

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