Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Split T7 RNA polymerase biosensors to study multiprotein interaction dynamics.

Methods in enzymology - 1 Jan 2020

Dewey Jeffrey A, Dickinson Bryan C

Abstract excerpt

Protein-protein interactions (PPIs) are involved in nearly all cellular processes. PPIs are particularly crucial for mediating selectivity along signaling pathways. Thus, measuring the competitive interplay between PPIs in a cell is important for both understanding fundamental cellular regulation and developing therapeutics targeting those whose dysregulation is associated with disease. A variety of split protein...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Bacteriophage T7
Share to Biosensing Techniques
Share to DNA-Directed RNA Polymerases

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Mutation

Share to Viral Proteins

Source

Open in PubMed Open full text

Identifiers

PMID: 32713533
DOI: 10.1016/bs.mie.2020.04.047
PMCID: PMC8211417

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Split T7 RNA polymerase biosensors to study multiprotein interaction dynamics.PMID 32713533Read ↗

Pooled PPIseq: screening the SARS-CoV-2 and human interface with a scalable multiplexed protein-protein interaction assay platformSemantic proximity Read ↗

Monitoring regulated protein-protein interactions using split TEVSemantic proximity Read ↗

Mutations at protein-protein interfaces: Small changes over big surfaces have large impacts on human health.Semantic proximity Read ↗

A T7 RNAP regulatory toolbox for cell-free network engineering and biosensing applicationsSemantic proximity Read ↗

A Phage-Assisted Continuous Selection Approach for Deep Mutational Scanning of Protein-Protein InteractionsSemantic proximity Read ↗

A Phage-Assisted Continuous Selection Approach for Deep Mutational Scanning of Protein-Protein Interactions.Semantic proximity Read ↗

A new protein-protein interaction sensor based on tripartite split-GFP association.Semantic proximity Read ↗

Multiplex mapping of protein-protein interaction interfacesSemantic proximity Read ↗

Analysis of Protein-Protein Interactions by Split Luciferase Complementation Assay.Semantic proximity Read ↗

A modular cell-free protein biosensor platform using split T7 RNA polymeraseSemantic proximity Read ↗

The split-hybrid system. Uncoding multiprotein networks and defining mutations that affect protein interactions.Semantic proximity Read ↗

Efficient cell-free evolution of RNA polymerases by droplet microfluidicsSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.