Article

Cell type-independent profiling of interactions between intracellular pathogens and the human phosphoproteome

2022-09-28

Abstract excerpt

Interactions between proteins from intracellular pathogens and host proteins in an infected cell are often mediated by post-translational modifications encoded in the host proteome. Identifying protein modifications, such as phosphorylation, that dictate these interactions remains a defining challenge in unraveling the molecular mechanisms of pathogenesis. We have developed a platform in engineered bacteria that d...

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Literature Corpus work: 70c1b9fb-d5b2-591f-9fb7-ff87caeeff7b
DOI: 10.1101/2022.09.27.509702

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