Article

Dual role of striatal astrocytes in behavioral flexibility and metabolism in the context of obesity

2023-03-23

Abstract excerpt

<h4>ABSTRACT</h4> Brain circuits involved in metabolic control and reward-associated behaviors are potent drivers of feeding behavior and are both dramatically altered in obesity, a multifactorial disease resulting from genetic and environmental factors. In both mice and human, exposure to calorie-dense food has been associated with increased astrocyte reactivity and pro-inflammatory response in the brain. Althou...

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Literature Corpus work: fd6ed735-22e8-5cd2-80ce-9b9d93ada785
DOI: 10.1101/2023.03.21.533596

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