Article

Fat food exacerbates post-prandial hypothalamic inflammation involving GFAP+ cells and microglia

2019-11-12

Abstract excerpt

In humans, obesity was associated with brain inflammation and glial cell proliferation. Studies in rodents showed that glial cell proliferation occurs within 24 hours of high-fat diet (HFD) consumption, before obesity development. This proliferation was mainly observed in the hypothalamus (HT), a crucial brain structure for controlling body weight. Therefore, we sought to characterize the post-prandial HT inflamma...

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Literature Corpus work: 99b341fa-b511-52e0-83bf-41142f2da3be
DOI: 10.1101/835967

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