Article

Disrupting astrocyte signalling in the nucleus accumbens impairs incentive-driven instrumental actions

2026-01-13

Abstract excerpt

Astrocytes in the nucleus accumbens (NAC) core have been observed to undergo phenotypic changes associated with drug-seeking behaviour in both humans and animals. However, the role of NAC core astrocytes in non-drug-related instrumental behaviour remains poorly understood. To address this, we chemogenetically activated hM4Di receptors selectively expressed on NAC core astrocytes in rats during food-motivated decis...

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Literature Corpus work: 6cb0cd7c-a9dc-52d4-b956-8e526994a3fc
DOI: 10.64898/2026.01.12.699167

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