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Article

Obesity induces functional astrocytic leptin receptors in hypothalamus.

Brain : a journal of neurology - 1 Apr 2009

Hsuchou Hung, He Yi, Kastin Abba J, Tu Hong, Markadakis Emily N, Rogers Richard C, Fossier Paul B, Pan Weihong

Abstract excerpt

The possible role of astrocytes in the regulation of feeding has been overlooked. It is well-established that the endothelial cells constituting the blood-brain barrier transport leptin from blood to brain and that hypothalamic neurons respond to leptin to induce anorexic signaling. However, few studies have addressed the role of astrocytes in either leptin transport or cellular activation. We recently showed...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 19293246
DOI: 10.1093/brain/awp029
PMCID: PMC2668946

Genes

GFAP

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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