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Dopamine release in nucleus accumbens is under tonic inhibition by adenosine A <sub>1</sub> receptors regulated by astrocytic ENT1 and dysregulated by ethanol

2021-11-27

Abstract excerpt

<h4>ABSTRACT</h4> Striatal adenosine A 1 receptor (A 1 R) activation can inhibit dopamine release. A 1 Rs on other striatal neurons are activated by an adenosine tone that is limited by equilibrative nucleoside transporter 1 (ENT1) that is enriched on astrocytes and is ethanol-sensitive. We explored whether dopamine release in nucleus accumbens core is under tonic inhibition by A 1 Rs, and is regulated by ast...

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Literature Corpus work
bc0a5f4b-d014-5096-a443-fee03daaac14
DOI
10.1101/2021.11.27.470186
Open publication

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Dopamine release in nucleus accumbens is under tonic inhibition by adenosine A <sub>1</sub> receptors regulated by astrocytic ENT1 and dysregulated by ethanolDOI 10.1101/2021.11.27.470186
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