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Article

Long-Term Glucose Starvation Induces Inflammatory Responses and Phenotype Switch in Primary Cortical Rat Astrocytes.

Journal of molecular neuroscience : MN - 1 Nov 2021

Kogel Vanessa, Trinh Stefanie, Gasterich Natalie, Beyer Cordian, Seitz Jochen

Abstract excerpt

Astrocytes are the most abundant cell type in the brain and crucial to ensure the metabolic supply of neurons and their synapse formation. Overnutrition as present in patients suffering from obesity causes astrogliosis in the hypothalamus. Other diseases accompanied by malnutrition appear to have an impact on the brain and astrocyte function. In the eating disorder anorexia nervosa (AN), patients suffer from...

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Identifiers

PMID: 33580474
DOI: 10.1007/s12031-021-01800-2
PMCID: PMC8585803

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