Article

Citrullination regulates wound responses and tissue regeneration in zebrafish

2019-12-27

Abstract excerpt

Calcium signaling is an important early step in wound healing, yet how these early signals promote regeneration remains unclear. Peptidylarginine deiminases (PADs), a family of calcium-dependent enzymes, catalyze citrullination, a post-translational modification that alters protein function and has been implicated in autoimmune diseases. We generated a mutation in the single zebrafish ancestral pad gene, padi2,...

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Literature Corpus work: fce141a2-786d-53a8-9b99-d93cb8461066
DOI: 10.1101/2019.12.27.889378

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