Article

Imaginal disc growth factors are <i>Drosophila</i> Chitinase-like Proteins with roles in morphogenesis and CO <sub>2</sub> response

2022-06-30

Abstract excerpt

Chitinase-like proteins (CLPs) are members of the family 18 glycosyl hydrolases, which include chitinases and the enzymatically inactive CLPs. A mutation in the enzyme’s catalytic site, conserved in vertebrates and invertebrates, allowed CLPs to evolve independently with functions that do not require chitinase activity. CLPs normally function during inflammatory responses, wound healing, and host defense, but when...

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Literature Corpus work: 0acde156-9d14-5677-841d-5504fa6507ba
DOI: 10.1101/2022.06.29.498179

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