Article

Transcriptional and Cellular Response of hiPSC-derived Microglia-Neural Progenitor Co-Cultures Exposed to IL-6

2023-12-22

Abstract excerpt

Elevated interleukin (IL-)6 levels during prenatal development have been linked to increased risk for neurodevelopmental disorders (NDD) in the offspring, but the mechanism remains unclear. Human-induced pluripotent stem cell (hiPSC) models offer a valuable tool to study the effects of IL-6 on features relevant for human neurodevelopment in vitro . We previously reported that hiPSC-derived microglia-like cells (M...

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Literature Corpus work: fc69d25e-8230-5838-850a-d1747db0c7e3
DOI: 10.1101/2023.12.21.572748

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