Article

B Cell-specific METTL3 depletion exacerbates experimental autoimmune encephalomyelitis

2025-07-30

Abstract excerpt

<title>Abstract</title> <p> N6-methyladenosine (m <sup>6</sup> A), the most prevalent RNA modification, plays a pivotal role in regulating mRNA metabolism and cellular processes such as immune responses. Although the m6A methyltransferase METTL3 is known to regulate T-cell homeostasis and influence experimental autoimmune encephalomyelitis (EAE, a model for multiple sclerosis (MS)), its function within B cells...

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Literature Corpus work: fbfdb075-73b1-5f16-91af-bb70d7591387
DOI: 10.21203/rs.3.rs-7206859/v1

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