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Genome-wide DNA methylation changes in CD19+ B cells from relapsing-remitting multiple sclerosis patients

21 Nov 2018

Abstract excerpt

Abstract Multiple Sclerosis (MS) is an inflammatory and neurodegenerative disease of the central nervous system. The inflammatory process in MS is driven by both T and B cells and current therapies are targeted to each of these cell types. Epigenetic mechanisms may provide a valuable link between genes and environment. DNA methylation is the best studied epigenetic mechanism and is recognized as a potential...

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PMID: 30479356
DOI: 10.1038/s41598-018-35603-0

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