Article

Systems Analysis of Immune Changes after B-cell Depletion in Autoimmune Multiple Sclerosis

2024-02-09

Abstract excerpt

Multiple sclerosis (MS) is a complex genetically mediated autoimmune disease of the central nervous system where anti-CD20-mediated B cell depletion is remarkably effective in the treatment of early disease. While previous studies investigated the effect of B cell depletion on select immune cell subsets using flow cytometry-based methods, the therapeutic impact on patient immune landscape is unknown. In this study...

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Literature Corpus work: 966b64e4-09c5-551f-bd80-8e7cc5b1e2b1
DOI: 10.1101/2024.02.07.576204

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