Article

TRAP-based allelic translation efficiency imbalance analysis to identify genetic regulation of ribosome occupancy in specific cell types <i>in vivo</i>

2020-08-24

Abstract excerpt

The alteration of gene expression due to variations in the sequences of transcriptional regulatory elements has been a focus of substantial inquiry in humans and model organisms. However, less is known about the extent to which natural variation contributes to post-transcriptional regulation. Allelic Expression Imbalance (AEI) is a classical approach for studying the association of specific haplotypes with relativ...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: fbf6f75f-e75f-5182-9d1a-06a82a01ee5c
DOI: 10.1101/2020.08.24.265389

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

TRAP-based allelic translation efficiency imbalance analysis to identify genetic regulation of ribosome occupancy in specific cell types <i>in vivo</i>DOI 10.1101/2020.08.24.265389Read

Allelic imbalance sequencing reveals that single-nucleotide polymorphisms frequently alter microRNA-directed repression.Semantic proximity Read

Isoform-specific translational control is evolutionarily conserved in primatesSemantic proximity Read

Allele-resolved monosome and polysome sequencing identifies functional cis-acting variants affecting mRNA translation efficiencySemantic proximity Read

Polysomal profiling coupled to allele-specific proteomics reveals an EIF4H tranSNP allele possessing higher mRNA translation potentialSemantic proximity Read

Polysomal Profiling Coupled to Allele-Specific Proteomics Reveals an EIF4H TranSNP Allele Possessing Higher mRNA Translation Potential.Semantic proximity Read

Hierarchical analysis of RNA-seq reads improves the accuracy of allele-specific expression.Semantic proximity Read

A survey of allelic imbalance in F1 mice.Semantic proximity Read

Integrative analysis of RNA, translation and protein levels reveals distinct regulatory variation across humansSemantic proximity Read

Integrative analysis of RNA, translation, and protein levels reveals distinct regulatory variation across humans.Semantic proximity Read

Direct analysis of ribosome targeting illuminates thousand-fold regulation of translation initiationSemantic proximity Read

Variant ribosomal RNA alleles are conserved and exhibit tissue-specific expression.Semantic proximity Read

Allelic imbalance assays to quantify allele-specific gene expression and transcription factor binding.Semantic proximity Read