Article

Partitioning gene-based variance of complex traits by gene score regression

2020-01-09

Abstract excerpt

The majority of genome-wide association studies (GWAS) loci are not annotated to known genes in the human genome, which renders biological interpretations difficult. Transcriptome-wide association studies (TWAS) associate complex traits with genotype-based prediction of gene expression deriving from expression quantitative loci(eQTL) studies, thus improving the interpretability of GWAS findings. However, these res...

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Literature Corpus work: fbf5c60b-7069-5cf0-b02f-726857620149
DOI: 10.1101/2020.01.08.899260

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