Article

Integrating gene expression with summary association statistics to identify susceptibility genes for 30 complex traits

2016-09-01

Abstract excerpt

Although genome-wide association studies (GWASs) have identified thousands of risk loci for many complex traits and diseases, the causal variants and genes at these loci remain largely unknown. We leverage recently introduced methods to integrate gene expression measurements from 45 expression panels with summary GWAS data to perform 30 transcriptome-wide association studies (TWASs). We identify 1,196 susceptibili...

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Literature Corpus work: 9d207aed-7150-50bb-982f-e3e88fd893ea
DOI: 10.1101/072967

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