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Article

LPM: a latent probit model to characterize the relationship among complex traits using summary statistics from multiple GWASs and functional annotations.

Bioinformatics (Oxford, England) - 15 Apr 2020

Ming Jingsi, Wang Tao, Yang Can

Abstract excerpt

MOTIVATION: Much effort has been made toward understanding the genetic architecture of complex traits and diseases. In the past decade, fruitful GWAS findings have highlighted the important role of regulatory variants and pervasive pleiotropy. Because of the accumulation of GWAS data on a wide range of phenotypes and high-quality functional annotations in different cell types, it is timely to develop a...

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PMID: 31860024
DOI: 10.1093/bioinformatics/btz947

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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