Article

Reduced expression of C/EBPβ-LIP extends health- and lifespan in mice

2018-01-18

Abstract excerpt

Ageing is associated with physical decline and the development of age-related diseases such as metabolic disorders and cancer. Few conditions are known that attenuate the adverse effects of ageing, including calorie restriction (CR) and reduced signalling through the mechanistic target of rapamycin complex 1 (mTORC1) pathway. Synthesis of the metabolic transcription factor C/EBP β ‐LIP is stimulated by mTORC1, whi...

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Literature Corpus work: fbf13efc-fd2a-5a32-879d-fe1aa232ee4d
DOI: 10.1101/250100

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