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Article

Altered Metabolism and Lipodystrophy in the Early B-Cell Factor 1-Deficient Mouse

19 Feb 2010

Abstract excerpt

We previously reported that mice deficient for the transcription factor early B-cell factor (Ebf1) exhibit markedly increased numbers of osteoblasts, bone formation rate, and serum osteocalcin, but the bone marrow of Ebf1(-/-) mice is also striking in its increased marrow adiposity. The purpose of this work was to analyze the metabolic phenotype that accompanies the altered bone morphology of Ebf1(-/-) mice....

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Share to Adipokines, Inflammation, and Metabolic Diseases
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Identifiers

PMID: 20172967
DOI: 10.1210/en.2009-0987

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