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Article

Effect of a C/EBP gene replacement on mitochondrial biogenesis in fat cells.

Genes & development - 15 Aug 2004

Chiu Chih-Hsien, Lin Wen-Der, Huang Shao-Yong, Lee Ying-Hue

Abstract excerpt

CCAAT/enhancer-binding proteins, C/EBPalpha and C/EBPbeta, are required for fat cell differentiation and maturation. Previous studies showed that replacement of C/EBPalpha with C/EBPbeta, generating the beta/beta alleles in the mouse genome, prevents lipid accumulation in white adipose tissue (WAT). In this study, beta/beta mice lived longer and had higher energy expenditure than their control littermates due to...

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Source

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Identifiers

PMID: 15289464
DOI: 10.1101/gad.1213104
PMCID: PMC514177

Genes

EBP

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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