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A hemagglutinin and neuraminidase biased immunological memory shapes the dynamics of antibody responses to Influenza A virus

2024-03-15

Abstract excerpt

Influenza A virus (IAV) infection establishes a more diverse immunological memory to different viral proteins compared to vaccination. We hypothesized that the relative abundance of pre-existing immune memory to different viral antigens could skew post-infection antibody responses. To explore this, we generated mouse models with either an IAV hemagglutinin (HA)- or neuraminidase (NA)-biased immunological memory. W...

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Literature Corpus work
fb8bdcb8-ab3d-5807-8c14-a14b6da9d955
DOI
10.1101/2024.03.14.584765
Open publication

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A hemagglutinin and neuraminidase biased immunological memory shapes the dynamics of antibody responses to Influenza A virusDOI 10.1101/2024.03.14.584765
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