Article

Characterization of flagellar and toxin phase variation in <i>Clostridium difficile</i> ribotype 012 isolates

2018-01-30

Abstract excerpt

Clostridium difficile causes diarrheal diseases mediated in part by the secreted toxins TcdA and TcdB. C. difficile produces flagella that also contribute to motility and bacterial adherence to intestinal cells during infection. Flagellum and toxin gene expression are linked via the flagellar alternative sigma factor, SigD. Recently, we identified a “flagellar switch” upstream of the early flagellar biosynthesis...

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Literature Corpus work: fb8b13a5-a95d-5098-8c1b-e0e0b0d023fe
DOI: 10.1101/256883

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