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Phase variation of a signal transduction system controls <i>Clostridioides difficile</i> colony morphology, motility, and virulence

2019-07-02

Abstract excerpt

Recent work has revealed that Clostridioides difficile , a major cause of nosocomial diarrheal disease, exhibits phenotypic heterogeneity within a clonal population as a result of phase variation. Many C. difficile strains representing multiple ribotypes develop two colony morphotypes, termed rough and smooth, but the biological implications of this phenomenon have not been explored. Here, we examine the molecul...

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Literature Corpus work
ed432dda-4142-5712-aefb-395ca626b710
DOI
10.1101/690230
Open publication

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Phase variation of a signal transduction system controls <i>Clostridioides difficile</i> colony morphology, motility, and virulenceDOI 10.1101/690230
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