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The Role of Flagella in Clostridium difficile Pathogenesis: Comparison between a Non-Epidemic and an Epidemic Strain

23 Sept 2013

Abstract excerpt

Clostridium difficile is a major cause of healthcare-associated infection and inflicts a considerable financial burden on healthcare systems worldwide. Disease symptoms range from self-limiting diarrhoea to fatal pseudomembranous colitis. Whilst C. difficile has two major virulence factors, toxin A and B, it is generally accepted that other virulence components of the bacterium contribute to disease. C. difficile...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 24086268
DOI: 10.1371/journal.pone.0073026

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