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Flagellar switch inverted repeat impacts flagellar invertibility and varies <i>Clostridioides difficile</i> RT027/MLST1 virulence

2023-06-23

Abstract excerpt

<h4>SUMMARY</h4> Clostridioides difficile RT027 strains cause infections that vary in severity from asymptomatic to lethal, but the molecular basis for this variability is poorly understood. Through comparative analyses of RT027 clinical isolates, we determined that isolates that exhibit greater variability in their flagellar gene expression exhibit greater virulence in vivo . C. difficile flagellar genes are p...

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Literature Corpus work
5395d15b-152c-5b1f-ac8d-63c5560a37a6
DOI
10.1101/2023.06.22.546185
Open publication

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Flagellar switch inverted repeat impacts flagellar invertibility and varies <i>Clostridioides difficile</i> RT027/MLST1 virulenceDOI 10.1101/2023.06.22.546185
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