Article

Population size shapes the evolution of lifespan

2022-12-17

Abstract excerpt

Biological aging results from the age-dependent change in the force of natural selection, which increases the probability of germline variants that limit survival to accumulate in genes acting predominantly in late life 1 . The evolutionary mechanisms underlying the accumulation of neutral mutations and antagonistically pleiotropic gene variants that cause biological aging have been analyzed to date under the ass...

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Literature Corpus work: fb365cc2-2c52-5c8e-bc03-93c5337dc7ee
DOI: 10.1101/2022.12.17.520867

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