Article
Why organisms age: Evolution of senescence under positive pleiotropy?
BioEssays : news and reviews in molecular, cellular and developmental biology - 1 Jul 2015
Maklakov Alexei A, Rowe Locke, Friberg Urban
Abstract excerpt
Two classic theories maintain that aging evolves either because of alleles whose deleterious effects are confined to late life or because of alleles with broad pleiotropic effects that increase early-life fitness at the expense of late-life fitness. However, empirical studies often reveal positive pleiotropy for fitness across age classes, and recent evidence suggests that selection on early-life fitness can...
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