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Article

Population growth inflates the per-individual number of deleterious mutations and reduces their mean effect.

Genetics - 1 Nov 2013

Gazave Elodie, Chang Diana, Clark Andrew G, Keinan Alon

Abstract excerpt

This study addresses the question of how purifying selection operates during recent rapid population growth such as has been experienced by human populations. This is not a straightforward problem because the human population is not at equilibrium: population genetics predicts that, on the one ha...

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Share to Genetic Fitness

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 23979573
DOI: 10.1534/genetics.113.153973
PMCID: PMC3813877

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-23979573-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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