Article
Evolution, mutations, and human longevity: European royal and noble families.
Human biology - 1 Aug 1998
Gavrilova N S, Gavrilov L A, Evdokushkina G N, Semyonova V G, Gavrilova A L, Evdokushkina N N, Kushnareva Y E, Kroutko V N, Andreyev AYu
Abstract excerpt
The evolutionary theory of aging predicts that the equilibrium gene frequency for deleterious mutations should increase with age at onset of mutation action because of weaker (postponed) selection against later-acting mutations. According to this mutation accumulation hypothesis, one would expect...
Topics
- Adult
- Aged
- Aging
- Biological Evolution
- Europe
- Famous Persons
- Female
- Genealogy and Heraldry
- Genetic Variation
- Humans
- Longevity
- Male
- Middle Aged
- Mutation
- Paternal Age
- Pedigree
- Regression Analysis
- Selection, Genetic
